Current Silicone Lubricants Limit the Growth of Prefilled syringe applications: Syringes, unlike ampoules and vials, require a layer of lubricant inside the syringe barrel to facilitate the easy movement of the plunger. Silicone oil is the current industry standard for use as a syringe lubricant. However, silicone oil molecules in their unbound state can adversely interact with the drug medium, rendering the medium ineffective. This fact limits the growth of the Prefilled syringe market. TriboGlide® is particularly advantageous in the biologics and insulin Prefilled applications, making what was impossible, possible.
TriboGlide® overcomes these problems because it is immobile and inert. The results include 80% lower particulates in the drug medium compared to standard silicone based systems. Click here to view a side-by-side comparison.
Mean Particulate count per cc of saline
10 cc Polypropylene syringe with butyl rubber stopper
FDA Approvals & Product Development
The TriboGlide® coating system has received FDA Approval under a 510K status for disposable hypodermic syringes. All ISO10993 biocompatibility testing mandated by the FDA for externally communicating medical devices has been completed. A broad range of patents have been filed in the U.S., Europe and Japan. Drug candidates are currently undergoing stability testing with the TriboGlide® platform. We welcome your new or existing product for testing and performance evaluation with TriboGlide®.